Amide Technologies

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Research Associate/Technician - Peptide Chemistry

  • R&D
  • Full-time
  • Cambridge, MA

2021-11-17 18:34:44 UTC

Description

Amide Technologies is reimagining how proteins and protein therapeutics are discovered, engineered, and applied. We use cutting-edge artificial intelligence and solid-phase flow chemistry to rapidly design and build proteins from the ground up. Amide’s engineered proteins and protein therapeutics are fully untethered from biological systems and contain unlimited non-natural amino acids, post-translational modifications, and artificial backbones.

Role description:

We are seeking an exceptional individual to join our growing team as a Research Associate/Technician. The successful candidate will be a key contributor to various research projects and be responsible for executing laboratory experiments, analyzing and reporting results, and working within a larger team on a regular basis. Applicants should be team players able to excel in a fast-paced, collaborative environment.

In this role you:

  • Use proprietary flow chemistry synthesis technology to synthesize next-gen peptides/proteins

  • Use LCMS, Flash, HPLC and FPLC instrumentation to purify/analyze peptides and proteins

  • Use biophysical and functional techniques like DSF, CD, and BLI to validate protein fold/activity

  • Troubleshoot challenging technical, experimental, and instrumental issues

  • Meticulously record and analyze data

  • Prepare and maintain laboratory reagents and instruments

  • Regularly discuss progress of work

Who you are:

  • BS or MS degree or equivalent experience in chemistry, chemical engineering, biochemistry, or related field

  • May have experience in organic synthesis including solid-phase peptide synthesis

  • May have experience in LC-MS, mass spectrometry, HPLC, FPLC, UV-VIS, NMR, FT-IR or related techniques

  • May have experience in recombinant protein expression and purification

  • May have experience in DSF, CD, BLI, SPR, ITC, or related instrumentation

  • Excellent written and verbal communication skills

  • Enthusiasm, independence, and a willingness to learn in a fast-paced, team environment

  • Committed to working collaboratively with an interdisciplinary team


Amide deeply values diversity and is committed to creating an inclusive environment for all employees. We are an equal opportunity employer. We consider all qualified applicants equally for employment. We do not discriminate on the basis of race, color, national origin, ancestry, citizenship status, protected veteran status, religion, physical or mental disability, marital status, sex, sexual orientation, gender identity or expression, age, or any other basis protected by law, ordinance, or regulation. 

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